Publications
| Title | Journal | Date |
Driver Project | Abstract |
|---|---|---|---|---|
|
Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries |
Nature Human Behaviour | Feb 2023 | DP2-iPOP | Preterm birth (PTB) is the leading cause of infant mortality worldwide. Changes in PTB rates, ranging from −90% to +30%, were reported in many countries following early COVID-19 pandemic response measures (‘lockdowns’)… |
| Lancet Global Health | Oct 2022 | DP – CHAIN | The transmission dynamics of influenza were affected by public health and social measures (PHSMs) implemented globally since early 2020 to mitigate the COVID-19 pandemic. We aimed to assess the effect of COVID-19 PHSMs on the transmissibility of influenza viruses and to predict upcoming influenza epidemics… | |
|
Data capture and sharing in the COVID-19 pandemic: a cause for concern |
Lancet Digital Health | Sept 2022 | DP1-EFCT | Routine health care and research have been profoundly influenced by digital-health technologies. These technologies range from primary data collection in electronic health records (EHRs) and administrative claims to web-based artificial-intelligence-driven analyses… |
| Effect of the COVID-19 pandemic on health service utilization across regions of Ethiopia: An interrupted time series analysis of health information system data from 2019–2020 | PLOS Global Public Health | Sept 2022 | DP – REHCORD | The spread of COVID-19 and associated deaths have remained low in Ethiopia. However, the pandemic could pose a public health crisis indirectly through disruptions in essential health services… |
|
|
The Lancet Regional Health Americas |
August 2022 | DP-EFFECT BRAZIL | There is limited information on the inequity of access to vaccination in low-and-middle-income countries during the COVID-19 pandemic. Here, we described the progression of the Brazilian immunisation program for COVID-19, and the association of socioeconomic development with vaccination rates, considering the potential protective effect of primary health care coverage… |
| ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19
|
Nature Scientific Data |
July 2022 | DP-ISARIC | The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19… |
|
Wiley online library |
June 2022 | DP – ACCORD | The objective was to compare COVID-19 outcomes in the Omicron-driven fourth wave with prior waves in the Western Cape, assess the contribution of undiagnosed prior infection to differences in outcomes in a context of high seroprevalence due to prior infection and determine whether protection against severe disease conferred by prior infection and/or vaccination was maintained… | |
|
|
International Journal of Infectious Diseases |
May 2022 | DP-ACCORD | At present, it is unclear whether the extent of reduced risk of severe disease seen with SARS-Cov-2 Omicron variant infection is caused by a decrease in variant virulence or by higher levels of population immunity… |
| Overcoming disruptions in essential health services during the COVID-19 pandemic in Mexico
|
BMJ Global Health |
Mar 2022 | DP-REHCORD | Significant disruptions in health services during the first year of the COVID-19 pandemic prompted the Mexican Institute of Social Security (IMSS) to implement the National Strategy for Health Services Recovery (NHSR strategy) to ensure resumption of essential health services provided to almost 68 million IMSS affiliates… |
|
Clinical Microbiology and Infection |
Mar 2022 | DP-EFFECT | To estimate the vaccine effectiveness after first and second dose of ChAdOx1 nCoV-19 against symptomatic COVID-19 and infection in a socially vulnerable community in Brazil when Gamma and Delta were the predominant variants circulating… | |
|
COVID-19 and resilience of healthcare systems in ten countries
|
Nature Medicine |
Mar 2022 | DP-REHCORD | Declines in health service use during the Coronavirus Disease 2019 (COVID-19) pandemic could have important effects on population health. In this study, we used an interrupted time series design to assess the immediate effect of the pandemic on 31 health services… |
|
Modeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India
|
Nature Magazine |
Feb 2022 | DP-CHAIN | Given global Coronavirus Disease 2019 (COVID-19) vaccine shortages and inequity of vaccine distributions, fractionation of vaccine doses might be an effective strategy for reducing public health and economic burden, notwithstanding the emergence of new variants of concern… |
|
Reproduction Numbers of SARS-CoV-2 Variants: A Systematic Review and Meta-analysis |
Oxford Academic |
Feb 2022 | DP-CHAIN | The COVID-19 pandemic continues to pose substantial risks to public health, worsened by the emergence of SARS-CoV-2 variants which may have a higher transmissibility and reduce vaccine effectiveness… |
|
Journal of Virological Methods |
Jan 2022 | DP-ACCORD | Routine SARS-CoV-2 surveillance in the Western Cape region of South Africa (January-August 2021) found a reduced RT-PCR amplification efficiency of the RdRp-gene target of the Seegene, Allplex 2019-nCoV diagnostic assay from June 2021 when detecting the Delta variant… | |
| Disruption in essential health services in Mexico during COVID-19: an interrupted time series analysis of health information system data | BMJ Global Health | Aug 2021 | DP-REHCORD | The COVID-19 pandemic has disrupted health systems around the world. The objectives of this study are to estimate the overall effect of the pandemic on essential health service use and outcomes in Mexico, describe observed and predicted trends in services over 24 months, and to estimate the number of visits lost through December 2020 |
| Pacifying A Pandemic With Numbers | Invivo – Informa Pharma Intelligence | Jun 2021 | DP1-EFCT | Powered by prominent global health philanthropies and the UK’s world-class collaborative capabilities in disease surveillance, the new International COVID-19 Data Alliance (ICODA) is gearing up to address a crucial – and yet unanswered – policy question for public health: can sharing data curated from a diversity of sources provide the hard evidence needed to improve patient outcomes against the virus – not just for today’s pandemic, but for future ones as well? Much will depend on a robust response from big pharma… |
|
The urgent need for better coordination across the global data sharing landscape |
ICODA | Jun 2021 | ICODA | Mapping of the landscape of COVID-19 data-related activities |
Articles
| Title | Journal | Date |
Driver Project | Abstract |
|---|---|---|---|---|
| Translating data in a pandemic | Lancet Digital Health | Sept 2022 | DP1-EFCT | During the global COVID-19 pandemic, researchers and clinicians have investigated how best to leverage technology and big data to provide virtual clinical care, model the effect of health policies on transmission, identify novel therapeutic treatments, and more… |
| Aridhia | May 2022 | DP-RASUP | One of several driver projects from Brazil-based Oswaldo Cruz Foundation (Fiocruz), this one is led by a team of four: lead PI Juliane Oliveira, a mathematician and researcher at Fiocruz and at the Universidade do Porto (Portugal)… | |
|
Assessing the spread risk of COVID-19 associated with multi-mode transportation networks in China |
Science Direct | April 2022 | DP-CHAIN | The spatial spread of COVID-19 during early 2020 in China was primarily driven by outbound travelers leaving the epicenter, Wuhan, Hubei province… |
| Aridhia | Mar 2022 | DP-PIH CovCo | This driver project from Partners In Health and Harvard Medical School looks to examine how the pandemic has impacted the care received by chronic care patients in four countries: Haiti, Malawi, Mexico and Rwanda… | |
|
Grand Challenges ICODA Data Science Initiative – Blog 1
|
Aridhia | Nov 2021 | DP-CHAIN | A few months ago, we reported on the launch of the Grand Challenges ICODA Data Science initiative by the Bill & Melinda Gates Foundation. These 10 projects will use the ICODA Workbench (powered by Aridhia’s DRE) to explore the answers to critical research questions relating to COVID-19. Over the coming weeks, we will take a look at some of these projects and what they aim to achieve… |
|
Data and Analytics – Put your expertise to work to address the COVID-19 pandemic |
Biopharmaceutical report | Sep 2021 | DP1-EFCT | The worldwide toll of the COVID-19 pandemic is substantial, so is the response of the many professionals in healthcare. Be it in the patient care, research or government sectors, many talented experts have joined together to advance the development of treatments to
address infections from the virus |
| Nature | Aug 2021 | DP2-iPOP | The disruption that the coronavirus has caused to daily life has created unique research opportunities for scientists | |
| Clinical and Investigative Medicine | June 2021 | DP2-iPOP | Meghan Azad and Nathalie Rodriguez share share their Top 10 Tips for defining and achieving success in Team Science | |
|
The international Perinatal Outcomes in the Pandemic (iPOP) study: protocol |
Wellcome Open Research | Feb 2021 | DP2-iPOP | Preterm birth is the leading cause of infant death worldwide, but the causes of preterm birth are largely unknown… |
|
Open Science to Address COVID-19: Sharing Data to Make Our Research Investment Go Further |
Springer Nature | Dec 2020 | DP1-EFCT | Over 1000 randomized clinical trials (RCTs) for the treatment and prevention of COVID-19 have been initiated. With access to the data from RCTs, researchers can integrate and summarize findings, evaluate new hypotheses, design future trials, and prioritize the next research questions to be addressed… |
| The Lancet | Oct 2020 | DP2-iPOP | As co leads of the new international Perinatal Outcomes in the Pandemic (iPOP) Consortium, we are delighted that the Lancet Small Vulnerable Newborn Series1 will focus crosssector attention on the high burden of baby deaths (encompassing miscarriage, stillbirth, and neonatal mortality) and disability (following preterm birth and low birthweight), which remain largely intractable with current siloed approaches… |
Pre-prints
| Title | Journal | Date |
Driver Project | Abstract |
|---|---|---|---|---|
| medRXiv | Nov 22 | DP-PRIEST | Uneven vaccination and less resilient health care systems mean hospitals in LMICs are at risk of being overwhelmed during periods of increased COVID-19 infection. Risk-scores proposed for rapid triage of need for admission from the emergency department (ED) have been developed in higher-income settings during initial waves of the pandemic… | |
| iScience | Oct 22 | DP-CHAIN | Although open-access data are increasingly common and useful to epidemiological research, the curation of such datasets is resource-intensive and time-consuming. Despite the existence of a major source of COVID-19 data, the regularly disclosed case reports were often written in natural language with an unstructured format | |
| medRXiv | Oct 22 | DP-ACCORD | Mortality occurred in 5.7% (95% CI: 5.3,6.0) of 17 831 first diagnosed infections. Higher mortality was associated with lower recent CD4, no evidence of ART collection, high or unknown recent viral load (among those with ART evidence), and recent first HIV evidence, differentially by age… | |
| medRXiv | Aug 2022 | DP-PRIEST | Tools proposed to triage acuity in suspected COVID-19 in the ED have been derived and validated in higher-income settings during early waves of the pandemic. We estimated the accuracy of seven risk-stratification tools recommended to predict severe illness in the Western Cape, South Africa… | |
|
|
medRXiv | Jul 2022 | DP – ACCORD | We aimed to compare clinical severity of Omicron BA.4/BA.5 infection with BA.1 and earlier variant infections among laboratory-confirmed SARS-CoV-2 cases in the Western Cape, South Africa, using timing of infection to infer the lineage/variant causing infection… |
| Profile of COVID-19 in Brazil: Risk Factors and Socioeconomic Vulnerability Associated with Disease Outcome
|
The Lancet | April 2022 | DP-RASUP | Background: COVID-19 spread at different rates across the globe, and severe outcomes of the disease are influenced by clinical and socioeconomic elements… |
| SSRN | Mar 2022 | DP-CHAIN | Although open-access data are increasing common and useful to epidemiological research, curation of such datasets is resource-intensive and time-consuming… | |
| medRXiv | Jan 2022 | DP-ACCORD | We aimed to compare COVID-19 outcomes in the Omicron-driven fourth wave with prior waves in the Western Cape, the contribution of undiagnosed prior infection to differences in outcomes in a context of high seroprevalence due to prior infection, and whether protection against severe disease conferred by prior infection and/or vaccination was maintained. | |
| medRXiv | Jan 2022 | DP-ACCORD | Emerging data suggest that SARS-CoV-2 Omicron variant of concern (VOC)is associated with reduced risk of severe disease. The extent to which this reflects a difference in the inherent virulence of Omicron, or just higher levels of population immunity, is currently not clear. | |
| medRXiv | Oct 2021 | DP-ACCORD | A novel proxy for the Delta variant, RNA-dependent RNA polymerase target delay in the Seegene Allplex™ 2019-nCoV PCR assay, was associated with higher mortality (adjusted Odds Ratio 1.45 [95%CI 1.13-1.86]), compared to presumptive Beta infection, in the Western Cape, South Africa (April-July 2021). Prior diagnosed infection and vaccination were protective. |
Generic governance processes for re-use
These process documents were created as part of the ICODA programme. They are open, free to use and amend as needed by your organisation, we just request you attribute us following our Attribution Policy.
Generic data controllership agreements for re-use
These agreements were created as part of the ICODA programme. They are open, free to use and amend as needed in support of establishing your organisation as a data controller, we just request you attribute us following our Attribution Policy. You can find background to this capability and the agreements used as part of the ICODA programme and generic versions provided for re-use on our data controllership page.
Digital Object Identifiers (DOIs)
Digital Object Identifiers (DOIs) were created for assets as part of the ICODA programme, ensuring they are always findable.
Datasets
Details of the datasets used by researchers as part of the ICODA programme can be found on the ICODA Gateway and HDR Innovation Gateway