DP EFFECT BRAZIL aimed to quantify the real-world value of COVID-19 vaccines in Brazil for protecting the individuals and the whole population by using statistical and machine-learning approaches on data from patients and from an existing COVID-19 mobile application.
To quantify the real-world value of COVID-19 vaccines in Brazil for protecting the individuals and the whole population by using statistical and machine-learning approaches on data from patients and from an existing COVID-19 mobile application.
Fernando Bozza at Fiocruz in Brazil and colleagues aimed to quantify the real-world value of COVID-19 vaccines in Brazil for protecting individuals from severe disease and for protecting the entire population from being infected. Knowing how effective vaccination is, and how durable the response in the real world is, particularly in low- and middle-income countries, is critical for ending the pandemic. They aimed to determine the effectiveness of the vaccine for protecting individuals using an approach called test-negative design together with statistical and machine learning approaches to compare the severity of respiratory disease in COVID-19 patients from 43 hospitals. At the population level, they performed an ecological study, and use regression analysis accounting for inequities to vaccine access, to measure the effect of vaccinations on COVID-19 cases, hospitalisations, and deaths.
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Date | Type | Abstract |
| The Lancet Regional Health | Aug 2022 | Publication | here is limited information on the inequity of access to vaccination in low-and-middle-income countries during the COVID-19 pandemic. Here, we described the progression of the Brazilian immunisation program for COVID-19, and the association of socioeconomic development with vaccination rates, considering the potential protective effect of primary health care coverage. | |
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What we talk about when we talk about COVID-19 vaccination campaign impact: a narrative review |
Frontiers in Public Health | May 2023 | Publication | The present work presents a narrative review, describing and discussing COVID-19 vaccination impact studies, mapping their relevant characteristics, such as study design, approaches and outcome variables, while analyzing their similarities, distinctions, and main insights. |
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Clinical Microbiology and Infection |
Mar 2022 | Publication | To estimate the vaccine effectiveness after first and second dose of ChAdOx1 nCoV-19 against symptomatic COVID-19 and infection in a socially vulnerable community in Brazil when Gamma and Delta were the predominant variants circulating… | |
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Gates Open Research |
Fed 2023 | Pre-print | Here, we present the protocol for a community-based prospective cohort study in the largest complex of favelas (slums) in Rio de Janeiro, Brazil (Complexo da Maré). The study participants are residents initially recruited during a massive vaccination campaign in the community. | |
| Seroepidemiology of SARS-CoV-2 on a partially vaccinated island in Brazil: determinants of infection and vaccine response |
Frontiers in Public Health |
Nov 2022 | Publication |
A vaccination campaign targeted adults in response to the pandemic in the City of Rio de Janeiro.We aimed to evaluate the seroprevalence of SARS-CoV-2 antibodies and identify factors associated with seropositivity on vaccinated and unvaccinated residents. We performed a seroepidemiologic survey in all residents of Paquetá Island, a neighborhood of Rio de Janeiro city, during the COVID-19 vaccine roll-out. |
| What did you do to stay ‘sane’ during the pandemic? A qualitative study to identify self-care mental health strategies utilized in a vulnerable population |
Gates Open Research |
Jul 2022 | Pre-print |
Mental health has deteriorated during the COVID-19 pandemic. These impacts are likely to be more severe in socially vulnerable communities. During March and April 2021, we conducted open-ended interviews with 317 community members in Complexo de Favelas da Maré, Rio de Janeiro, Brazil, one of the largest slum areas in South America… |
| The resilient intensive care unit |
Springer Open |
Apr 2022 | Publication |
The COVID-19 pandemic tested the capacity of intensive care units (ICU) to respond to a crisis and demonstrated their fragility. Unsurprisingly, higher than usual mortality rates, lengths of stay (LOS), and ICU-acquired complications occurred during the pandemic. However, worse outcomes were not universal nor constant across ICUs and significant variation in outcomes was reported, demonstrating that some ICUs could adequately manage the surge of COVID-19… |
| Title | Type | Description |
| GitHub codebase | Code | Code scripts produced during the development of research outputs and community engagement activities are available in a GitHub repository from the research team (Centre for Healthcare Operations and Intelligence “NOIS”) |
| Brazilian Vaccination, Deaths, Cases in a Municipality Level | Metadata | Data from Brazil’s vaccination programme, as well as deaths and cases at a municipality level, and was analysed in one of our research papers |
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| Documentary: Vacina Maré initiative |
During the campaign, research was started that will monitor, for at least two years, the effectiveness of the vaccine, the circulation of variants of the coronavirus and Covid Longa in the territory. The #VacinaMaré campaign is an initiative of Fiocruz, the Municipal Health Secretariat of Rio de Janeiro and Redes da Maré.
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Documentary: community engagement experience in Complexo da Maré |
One of the most relevant field surveys carried out in the world on the behavior of the coronavirus and its variants, the effectiveness of the vaccine and the consequences of Covid-19 among the population takes place in Maré.
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The dashboard was designed as a dashboard monitor for COVID-19 data in Brazil that included data on Cases, Deaths, Hospitalizations, and Vaccination in the country. The dashboard comprised interactive time-series plots and spatial analysis |
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The dashboard provides an overview of the total number of cases and deaths in the favelas of Maré, Manguinhos and the city of Rio de Janeiro. This dashboard was developed to assist partners during the Vacina Maré and Conexão Saúde projects |
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An online dashboard that monitors the number of COVID-19 hospital admissions in Brazil. The app reads data directly from the Brazilian National Epidemiological Surveillance System (SIVEP-Gripe) and is automatically updated every week. |
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Website for the Effect project and the The Vacina Maré survey: an initiative of Fiocruz, in partnership with Redes da Maré and the Rio City Hall, and its main objective is to estimate the effectiveness of the vaccine against Covid-19 and the impact of the pandemic in the territory of Maré, in Rio of January.
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Brazil’s Favelas Offer Lessons in Building Public Trust |
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