Transparency Reporting

We are committed to transparency across all our activities.  This page provides information about research projects that have been approved to use data in the ICODA Workbench, with information about the lead researchers.

 

graphic of information flying around the world blue curved line blue curved line

Approved Proposals

The ICODA initiative remains in a driver project mode of operation currently, with these projects helping to shape our processes, tools and ways of working.  Our driver projects were funded when the ICODA initiative was set up initially or were selected as part of a Gates Foundation Grand Challenges ICODA open funding call, which launched in December 2020, with grant awards announced in July 2021.  You can find our approved projects below, all of which are focused on COVID-19.  All of our project teams are very open to collaboration with researchers working in parallel or adjacent areas where co-working can be of public benefit.

 

Request ID Lead Researcher(s) Lead Institution(s)  Approval date Research Proposal
001 Sarah Stock

Meghan Azad

Natalie Rodriguez

Merilee Brockway

David Burgner

Helga Zoega

University of Edinburgh, University of Manitoba, Murdoch Children’s Research Institute, University of New South Wales 10 Mar 2021 Describe trends and regional differences in preterm births (PTB) and stillbirth during COVID-19 pandemic lockdowns globally, using population-representative aggregate data and standardized outcome definitions.

https://icoda-research.org/project/dp2-ipop/

002 Fernando Bozza Fiocruz 5 May 2021 Real-world value of COVID-19 vaccines in Brazil for protecting individuals from severe disease and for protecting the entire population from being infected

https://icoda-research.org/project/dp-effect-brazil/

003 Catherine Arsenault Harvard T.H. Chan School of Public Health 5 May 2021 Effect of the COVID-19 pandemic and associated containment policies such as curfews on the quality of health care in seven countries and the rates of mortality from non-COVID conditions

https://icoda-research.org/project/dp-rehcord/

004 Andrew Boulle University of Cape Town 5 May 2021 Study the clinical epidemiology and evolution of a new variant of SARS-CoV-2 that emerged in South Africa and the impact on patients with existing health conditions

https://icoda-research.org/project/dp-accord/

005 Luis Felipe Reyes Universidad de La Sabana 5 May 2021 Standardised strategy for researchers to better utilise the ISARIC-COVID-19 dataset, which consists of over 520,000 hospitalised patients from more than 62 countries, in order to identify the causes and health impacts of severe complications arising from COVID-19 infection.

https://icoda-research.org/project/dp-isaric/

006 Xiaofan Liu City University of Hong Kong 5 May 2021 Reconstruct COVID-19 transmission chains between individuals in communities and households using statistical methods applied to existing datasets to more reliably estimate COVID-19 transmission characteristics, such as reproduction rates, that are critical for planning effective control measures

https://icoda-research.org/project/dp-chain/

007 Maria Yury Ichihara Fiocruz 5 May 2021 Create a social disparities index to measure inequalities relevant to the COVID-19 pandemic, such as unequal access to healthcare, to identify regions that are more vulnerable to infection and to better focus prevention efforts

https://icoda-research.org/project/dp-ids-covid19/

008 Kirsty Le Doare MRC/UVRI & LSHTM Uganda Research Unit 5 May 2021 Develop a model using data collected in real-time to identify the risk factors for adverse pregnancy and infant outcomes caused by the COVID-19 pandemic that can be used to rapidly inform interventions

https://icoda-research.org/project/dp-iroc/

009 Juliane Foseca de Oliveira Fiocruz 5 May 2021 Develop mathematical and statistical methods to model COVID-19 transmission across populations in Brazil to better inform local intervention efforts. This study will use existing health data and social and economic determinants for over 5,500 Brazilian cities, as well as data relating to mitigation strategies and social mobility patterns. These will be used to develop and apply statistical analyses and nonlinear mathematical modelling to forecast disease outcomes, which consider specific socio-economic  conditions that influence transmission rates

https://icoda-research.org/project/dp-rasup/

010 Dale Barnhart Partners in Health of Haiti, Malawi, Mexico, and Rwanda 5 May 2021 Determine how the COVID-19 pandemic has impacted health care provision and utilisation for patients with HIV, heart disease, and diabetes, and the health outcomes of these patients, in all four countries

https://icoda-research.org/project/dp-pih-covco/

011 Carl Marincowitz University of Sheffield 5 May 2021 Develop a risk assessment tool to help emergency clinicians quickly decide whether a patient with suspected COVID-19 needs emergency care or can be safely treated at home to avoid overburdening hospitals particularly in low- and middle- income countries (LMICs)

https://icoda-research.org/project/dp-priest/

012 Hwanhee Hong

Susan Halabi

Duke University 29 July 2021 What is the best treatment to treat COVID-19 patients? By combining evidence from published COVID-19 trials via Bayesian multivariate network meta-analysis, we will compare and rank treatments with respect to prespecified multiple endpoints (e.g. mortality, hospitalization, ventilation, relieve of symptoms).

https://icoda-research.org/project/dp1-efct/

013 Nevine Zariffa NMD Group 28 Sept 2021 Interrogation of Drug Classes for the Treatment of COVID19 based on Randomised Controlled Trial Data. What level of Data and Analytics is required for such an endeavour?

https://icoda-research.org/project/dp1-efct/

014 Jaap Mandema Certara 28 Sept 2021 Interplay between RWD (real world data) and RCT (randomised clinical trial) results to streamline drug repurposing for pandemic viral disease.

https://icoda-research.org/project/dp1-efct/

015 Jenn Visich Gates Foundation 28 Sept 2021 Can we form a re-useable drug repurposing framework?

https://icoda-research.org/project/dp1-efct/

016 Jonas Haagstrom Cytel 28 Sept 2021 Methodologies to address evolution of standard of care over time

https://icoda-research.org/project/dp1-efct/

017        

 

Rejected proposals

We will also publish information about any applications that are not approved here, together with information about the reason.

With over 400 applications received, the call for Grand Challenges ICODA pilot projects was subject to a rigorous multi-stage review, involving an international review panel.  The successful projects all address major research questions relating to COVID-19, which seek to have major impact in both the current and future pandemics, and focus on rapid, innovative secondary analysis of data to produce insights that will have major public benefit.

 

Request ID Lead Researcher Institution Research Proposal Rejection Rationale